Toxicological issues related to packaging
Ningbo XISXI E-commerce Co., Ltd , https://www.petspetsproducts.com
First, toxicology analysis and research related to packaging
First, the existence of toxic substances. Can be roughly divided into the following three situations:
1 The substance itself is toxic. For example, various pesticides, household pesticides, etc., many heavy metals such as lead, cadmium, mercury, arsenic and other chemical materials such as stupid, formaldehyde, cyanide, etc. are toxic, and some are highly toxic. These poisons must be properly packaged. And in the packaging process, try not to let the human body directly contact these substances. 
2 The toxic substances contained in the product will volatilize and pollute the air during use. This situation is more common in the packaging industry. Paints and glues are commonly used in the packaging industry. Which may contain a variety of heavy metals and organic volatiles. Organic-based volatiles, such as formaldehyde, may be used in wood-based panels and paperboard, which are easily volatilized when molded into packages. Again, pigments used in making containers from crystal glass are often toxic. Making and using pottery can lead to problems with lead and cadmium poisoning. When making metal containers, you will encounter leaded solders and so on. 
3 The product itself is not toxic, but it will produce toxic substances under certain conditions. Such as chemical reactions with other substances or thermal decomposition and so on. Many plastics decompose at high temperatures, producing a variety of toxic substances. Commonly used packaging materials, such as the so-called "white pollution" foam, will produce toxins and damage the liver at temperatures above 60°C. If these materials are used for packaging, they must not be exposed to high temperatures. For example, automatic strapping machines can release harmful fumes when they are hot-melt adhesive plastic strapping, and they often run straight into the operator's eyes and mouth, irritating the operator’s eyes. And respiratory system. There is also a situation where these material packages are toxic to humans when used in food packaging. A common example is a normal polyethylene plastic bag. 
Second, the harm of toxic substances to human health. There are roughly the following situations:
1 Corrosive. Such as various acids and alkalis, various detergents, removers and so on. 2 irritating. Various volatile gases can irritate people's eyes, nose and mouth, throat, etc. It can sometimes cause allergies and rashes. 3 toxicity. Toxic substances can affect almost all organs and tissues throughout the body. Studies have shown that carbon monoxide, manganese, lead, mercury, methylmercury, etc. can damage the brain; carbon monoxide, sulfur dioxide, etc. will damage the heart; mercury and cadmium will damage the kidney; selenium, chlorinated hydrocarbons, etc. will damage the liver; fluorine, Lead, zinc, etc. can damage the bones; arsenic, bismuth, nickel, chromium, acid and alkali can damage the skin; chlorine and cadmium can damage the blood vessels; lead, fluoride, arsenic, vanadium, etc. can damage the intestine; fluorine and selenium can damage Teeth; Formaldehyde and other volatile gases can damage the eyes, nose, and throat; benzene can damage hematopoietic function; asbestos, dust, radon, sulfur dioxide, ammonia, cadmium, ozone, nickel carbonate, hydrogen sulfide, etc. can damage the lungs and so on. 4 radioactive. Many printing machines and detection equipment used in the packaging industry generate ionizing radiation. Nowadays, people are generally concerned about major toxicities to the human body, such as fatal or carcinogenic, while neglecting other forms of poisoning to people's physical and mental health, such as headache and lack of energy. 
Second, study the role of toxicological problems
1 It is beneficial to the physical and mental health of employees, reduces occupational diseases, and improves work efficiency, thereby improving the economic efficiency of enterprises. Can take effective and timely protective measures. Some small enterprises, when making cartons, use hand-based, hand-glued and glued cardboard, prone to benzene poisoning and formaldehyde poisoning. In pesticide plants, volatile pesticides and dust pesticides often have a greater toxic effect on the packaging industry. An important concept in toxicology research is the amount of poisoning. Strictly speaking, most substances are toxic at high doses, including vitamins, minerals, and aspirin. Some substances (such as fluorine) have effects on people's physical and mental health at certain doses, and when the dose exceeds a certain dose, the toxicity will be correspondingly weakened, and its effect on the physical and mental health of people is parabolic with the increase of dose. 
The purpose of carrying out packaging-related toxicological studies is to control the dose within an acceptable range. Toxic substances show different toxicity due to differences in race, sex, age, food structure, and physical condition. Therefore, it is very important to carry out research in this area in conjunction with the specific conditions in China. 
2 is conducive to improving the competitiveness of enterprises. The competitiveness of an enterprise is definitely not an abstract concept. It tangibly affects all aspects of the enterprise. At present, the emphasis on environmental protection has become the mainstream of the development of the world packaging industry. Many localities and enterprises in the purchase of goods, not only requires the product itself is not toxic, in line with the requirements of environmental protection, but also requires that the company's production environment and production process meet the requirements of environmental protection, no harm to the production workers. In addition, if someone else's product contains toxic substances and your product is non-toxic, you will be one step ahead in the market, especially in civilian products. 
3 to facilitate the organization of production management to prevent unnecessary accidents. 
Third, the main issues to be solved
There are many problems related to packaging that need to be solved urgently. For example, how to quickly and easily perform toxicological analysis of packaging materials. This problem deserves special attention when designing and manufacturing pharmaceutical packaging, because many medicines are chemicals themselves and are prone to chemical reactions. For example, when PVC is used as a medicine container, much work remains to be done in this regard. The reuse of recycling bottles, on the one hand, saves resources and is conducive to environmental protection; on the other hand, it also brings many toxicological problems. How to ensure that packaging recycling bottles are not contaminated by other toxic substances during recycling and recycling?
We all know that due to improper packaging, it will cause food rot and cause food poisoning. However, an important factor involved in determining the shelf life of foods using certain packaging (including packaging materials and packaging processes) is toxicological analysis. This is a problem that has been studied for a long time but has not been solved so far. Of course, there are various reasons for this, but one of the main reasons is that many manufacturers often attach great importance to the quality of the product itself, but they ignore the impact of packaging on product quality, and do not carry out the necessary scientific analysis and research in this regard. Only when using packaging, or using analogy, label the expiration date of their own products based on other similar packaging products; or use an estimation method to label the validity of packaging contents based on past experience. Of course, we cannot rule out the possibility of being completely blind. The result is that the shelf life of the actual product is longer than the label, or even a lot longer, which virtually reduces the competitiveness of the product; or conversely, the shelf life of the actual product is much shorter than the labeling, and the consumer is crippled. Take legal responsibility. 
There is also a situation where the original packaging material is temporarily out of stock. In order to deliver the goods, a temporary change of packaging materials results in undesirable toxicological indicators, resulting in a complete return and scrapping of products, resulting in huge losses. If the toxicological indicators of various packaging materials can be clearly marked, this will not happen. The current problem is that due to insufficient attention to toxicological issues related to packaging, some toxicological situations have not been clarified, and law enforcement has sometimes failed to be in place, and the labeling of packaging materials has been seriously inadequate, resulting in unavoidable economic losses. 
It is very important to carry out toxicology studies related to packaging. Never think that the study of toxicology has nothing to do with the packaging industry. It can be carried out independently and commissioned when necessary. In doing so, it is very likely that some important things have been ignored. To carry out toxicology studies related to the packaging industry, it is necessary to consider the packaging materials, processes, and economic costs in a comprehensive manner. It also involves legislation and law enforcement.